Kurimchak, A.M., Shelton, C., Duncan, K.E., Johnson, K., Brown, J., O'Brien, S., Gabbasov, R., Fink, L.S., Li, Y.S., Childers, W.E., Connolly, D.C., Chernoff, J., Peterson, J.R., Duncan, J.S. Adaptation of the kinome promotes resistance to BET bromodomain inhibitors in ovarian cancer. Cell Rep (in press).
Duong-Ly, K.C., Devarajan, K., Liang, S., Horiuchi, K.Y., Wang, Y., Ma, H., Peterson, J.R. (2016) Kinase inhibitor profiling reveals unexpected opportunities to inhibit disease-associated mutant kinases. Cell Rep 14(4):772-781. See the supporting Kinase Inhibitor Resource web tool
Xu Q., Malecka, K.L., Fink, L., Jordan, E.J., Duffy, E., Kolander, S., Peterson, J.R., Dunbrack, R.L. (2015) Identifying three-dimensional structures of autophosphorylation complex in crystals of protein kinases. Sci Signaling 8(405)rs13.
Vijayan R.S., He P., Modi V., Duong-Ly K.C., Ma H., Peterson J.R., Dunbrack R.L. Jr., Levy R.M. (2015) Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors. J Med Chem 58(1):466-479.
Fink, L.S., Beatty, A., Devarajan, K., Peri, S., Peterson, J.R. (2015) Pharmacological profiling of kinase dependency in cell lines across triple-negative breast cancer subtypes. Mol Cancer Ther 14:298-306.
Strochlic, T.I., Stavrides, K.P., Thomas, S.V., Nicolas, E., O'Reilly, A.M., Peterson, J.R. (2014) Ack kinase regulates CTP synthase filaments during Drosophila oogenesis. EMBO Rep 15(11):1184-1191.
Duong-Ly, K.C., Peterson, J.R. (2014) A high-throughput radiometric kinase assay. Methods Mol Biol 1360:87-95.
Chen, C., Ha, B.H., Thevenin, A.F., Lou, H.J., Zhang, R., Yip, K.Y., Peterson, J.R., Gerstein, M., Kim, P.M., Filippakopoulos, P., Knapp, S., Boggon, T.J., Turk, B.E. (2013) Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Mol Cell 53 (1): 140-147.
Anastassiadis, T.*, Duong-Ly, K.C.*, Deacon, S.W., Lafontant, A., Ma, H., Devarajan, K., Dunbrack, R.L. Jr., Wu, J., Peterson, J.R. (2013) A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-related kinase (ERK) inhibitor. J Biol Chem 288(39): 28068-28077. *equal contribution
Duong-Ly, K.C. and Peterson, J.R. (2013) The Kinome and Kinase Inhibition. Curr Protoc Pharmacol Chapter 2 (Unit 2.9).
Viaud, J. and Peterson, J.R. (2012) Identification of allosteric inhibitors of p21-activated kinase. Methods Mol Bio 928: 67-79.
Strochlic, T.I., Concilio, S., Viaud, J., Eberwine, R., Wong, L.E., Minden, A., Turk, B.E., Plomann, M., and Peterson, J.R. (2012) Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking. Proc Nat Acad Sci 109 (11): 4116-21.
Anastassiadis. T.,Deacon, S.W., Devarajan, K., Ma, H., and Peterson, J.R. (2011) Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nature Biotechnology29(11): 1039-1045. See the supporting Kinase Inhibitor Resource web tool
Strochlic, T.I., Viaud, J., Rennefahrt, U.E.E., Anastassiadis. T., and Peterson, J.R., (2010) Phosphoinositides are essential co-activators for p21-activated kinase 1 (Pak1). Molecular Cell 40(3):493-500.
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